3M Zeta Plus 16NZA Encapsulated Filter System

• Clarification of cell cultures and fermentation broths in biopharmaceutical production.
• Pre-filtration for sterile filtration steps to protect downstream membrane filters.
• Removal of aggregates and particulates in vaccine manufacturing.
• Processing of biologics, such as monoclonal antibodies and recombinant proteins.
• Small to medium-scale batch processing in research and development or pilot plants.

Filter media type

Typically advanced depth filtration media, often incorporating charge-modified materials for enhanced contaminant removal.

Housing material

Encapsulated systems commonly feature robust, medical-grade plastic housings for single-use applications.

Connection types

Units of this type typically utilise sanitary connections, such as tri-clamp or hose barb fittings, for easy integration into process lines.

Operating pressure

For this class of equipment, typical operating pressures are in the range of 0.5 to 3 bar, depending on the specific filter media and flow rate.

Typical capacity

Encapsulated filter systems like the 16NZA are designed for processing volumes ranging from several litres to hundreds of litres per batch, suitable for pilot to small-scale production.

Footprint

These systems are generally compact, designed for benchtop or mobile cart use, making them suitable for laboratory and small-scale manufacturing environments.

• What are the benefits of an encapsulated filter system?

  Encapsulated systems offer ease of use, reduced cleaning validation, and minimised operator exposure to process fluids, as the filter media is contained within a disposable housing.

• Is this system suitable for sterile applications?

• What maintenance is required for this type of unit?

• Can this system be used with different filter media grades?

• What kind of upstream equipment is typically needed?

Laboratory filtration systems are valued for reliability and durability, making them suitable for used purchase when sourced carefully. Buyers typically prioritise checking membrane and filter condition, as replacement costs can be significant. Industry sentiment favours systems from established manufacturers known for consistent performance. Common strengths include robust construction, compatibility with various applications, and availability of spare parts. When assessing used units, verifying maintenance history and operational specifications remains essential for ensuring continued performance in biotech and pharmaceutical environments.

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