Applikon Pilot System 50L Fermentation system

• Pilot-scale fermentation for biotechnology and pharmaceutical research and development.
• Small-batch production of enzymes, proteins, and other bio-products.
• Process optimisation and scale-up studies for industrial fermentation.
• Development of new microbial strains and fermentation protocols.

Typical capacity

This unit is specified at 50 litres. For this class of equipment, capacities commonly range from 30 litres to 100 litres.

Construction material

Units of this type, especially for pilot and production use, are typically constructed from stainless steel (e.g., 316L) for hygiene and corrosion resistance.

Control system

Pilot fermentation systems commonly feature integrated control systems for parameters such as pH, dissolved oxygen, temperature, and agitation speed.

Sterilisation method

For this class of equipment, sterilisation is typically achieved either in-situ (SIP) or via an autoclave for smaller components.

Power supply

Pilot systems commonly require a three-phase electrical supply, typically 400V, 50Hz in the UK, with specific amperage depending on heating and motor loads.

Footprint

The footprint for a 50L pilot system can vary, but typically requires a dedicated area of approximately 1.5m x 1.5m, plus space for ancillary equipment.

• What kind of utilities are typically required for a system like this?

  These systems commonly require electricity, chilled water for cooling, compressed air or process gases (e.g., nitrogen, oxygen), and a drain for waste liquids.

• Is this system suitable for both microbial and cell culture applications?

• What maintenance is typically involved with a used fermentation system?

• Can this system be integrated into a larger process line?

• Are spare parts readily available for Applikon systems?

Bioreactors and fermenters are valued for reliable performance in scaling bioprocess development and manufacturing. Buyers typically prioritise vessel integrity, sterilisation capability, and control system functionality when purchasing used equipment. Industry sentiment favours units with documented maintenance histories and calibrated instrumentation. Key strengths include robust construction and adaptability across multiple applications. Common considerations include sensor condition, heating and aeration systems, and compatibility with existing facility infrastructure. Equipment from established manufacturers generally commands buyer confidence for critical bioprocessing operations.

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