Sequencers & Ion Sequencing Systems

Ask for the total run count, the most recent run metrics and confirmation that the fluidics and optics or sensor path pass a self test. Verify the software licence transfers and that the reagents for that chemistry are still produced. A platform tied to a discontinued reagent line is a poor buy however sound the hardware.

Work out your reads per sample and sample numbers, then compare that against a platform's per run yield. Benchtop units suit targeted panels and small genomes, while production systems earn their cost on whole genome and high volume work. Buying more output than you use ties up capital in idle capacity.

A run is only as good as the libraries you load, so quantification and fragment sizing kit matters. Confirm you have or can source the prep chemistry and QC instruments for your chosen system. Balanced, well characterised libraries protect the value of every run.

Larger systems may need a stable ambient temperature, a dedicated power circuit and an uninterruptible supply for long runs. Some also need vibration free benching and specific network provision for data transfer. Ask the seller for the exact utility and space requirements before you plan the install.

Financing is offered on qualifying listings, which helps spread the substantial cost of a sequencing platform. When a listing includes finance, it is displayed there. You can also discuss it with the seller during your enquiry to see how it suits your budget.