Cytiva formerly GE Healthcare - Cytiva AxiChrom 100/500 Chromatography Column

• Pilot-scale purification of biopharmaceuticals such as antibodies, proteins, and vaccines.
• Development and optimisation of chromatography methods for larger-scale production.
• Separation and purification of various biomolecules in research and development settings.
• Production of clinical trial materials requiring high purity and reproducibility.

Column Diameter

Typically 100 mm for this model, indicating suitability for pilot-scale operations.

Column Length

Commonly 500 mm, allowing for a range of bed heights depending on application requirements.

Operating Pressure

Designed for low-pressure chromatography, typically up to 5 bar, suitable for soft gel media.

Materials of Construction

Typically pharmaceutical-grade polymers and stainless steel, ensuring chemical compatibility and hygiene.

Flow Rate

Variable, depending on media and back pressure, but designed for consistent flow in pilot applications.

Temperature Range

Commonly ambient to 40°C, suitable for most biopharmaceutical processes.

• What types of chromatography media are compatible with the AxiChrom 100/500?

  These columns are designed for a wide range of soft gel chromatography media, including ion exchange, size exclusion, affinity, and hydrophobic interaction resins.

• Is this column suitable for cGMP environments?

• What accessories are typically needed to operate this column?

• How is the bed height adjusted in an AxiChrom column?

• What maintenance is required for a used chromatography column?

Chromatography columns and accessories hold strong reputations within analytical laboratories for reliability and consistent performance. Buyers typically value used equipment that maintains original specifications and comes with documentation of maintenance history. Industry sentiment favours purchasing from reputable sources where column condition, packing integrity, and compatibility with existing systems are verified. Common strengths include durability of quality columns across multiple applications and cost savings versus new purchases. When buying used, inspecting for damage, confirming proper storage conditions, and verifying suitability for intended analytical methods remain critical considerations for laboratory operations.

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