Leica Reichert MM80 E Mirror Cryo Fixation Unit

• Rapid freezing of biological samples for electron microscopy.
• Preservation of tissue morphology for ultrastructural studies.
• Preparation of samples for freeze-fracture and freeze-etch techniques.
• Research in cell biology, neuroscience, and pathology requiring high-quality cryo-preservation.

Typical cooling method

Utilises a highly polished copper mirror cooled by liquid nitrogen.

Freezing rate

Extremely high cooling rates are achieved, typically in the range of 10,000 K/s or more, crucial for preventing ice crystal formation.

Sample size

Designed for very small biological samples, typically less than 1mm in diameter.

Power supply

Units of this type commonly require a standard laboratory power supply, often 230V, 50Hz.

Temperature range

The mirror can typically reach temperatures below -190°C.

Footprint

For this class of equipment, the footprint is generally compact, suitable for benchtop laboratory use.

• What is mirror cryo fixation?

  Mirror cryo fixation involves rapidly freezing a biological sample by bringing it into direct contact with a highly polished, extremely cold metal mirror, typically copper, cooled by liquid nitrogen. This method achieves very high cooling rates.

• Why is rapid freezing important for biological samples?

• What consumables are typically required for a cryo fixation unit?

• Can this unit be used for all types of biological samples?

• What maintenance does a unit like this typically require?

Cryo fixation units are valued in laboratories for preserving specimen integrity during processing. Buyers typically seek models offering reliable temperature control and rapid freezing capabilities. Used units warrant inspection of cooling systems, thermal consistency, and maintenance history, as performance degradation directly affects sample quality. Industry users appreciate equipment delivering uniform preservation results whilst minimising ice crystal formation. Key considerations include chamber capacity, defrost mechanisms, and compatibility with existing laboratory workflows. Established manufacturers generally command confidence amongst purchasers seeking dependable performance.

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