What is Tangential Flow Filtration (TFF)?

TFF is a filtration method where the feed stream flows tangentially across the membrane surface, reducing membrane fouling and allowing for continuous processing.

Why use a single-use TFF system?

Single-use systems eliminate the need for cleaning and sterilisation between batches, reducing turnaround time, labour costs, and the risk of cross-contamination.

What types of membranes are compatible with this system?

Pall Allegro TFF systems are designed to work with Pall's range of single-use TFF cassettes, which come in various pore sizes and materials for ultrafiltration and microfiltration.

Is this system suitable for GMP environments?

Single-use TFF systems are widely adopted in GMP-compliant biopharmaceutical manufacturing due to their controlled material quality and reduced contamination risk. Documentation for materials and validation support is typically available from the manufacturer.

What maintenance is required for a used single-use TFF system?

For the reusable hardware component, routine checks of pumps, sensors, and connections are advisable. The single-use flow path and cassettes are replaced after each use, minimising maintenance on process-contact parts.

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Used Pall Allegro 1/2" Single Use TFF System - Single-Use Bioprocess Systems

Máquina usada

Disponível

Vendedor verificado

Pall Allegro 1/2" Single Use TFF System

Name: Pall Allegro 1/2" Single Use TFF System
Brand: Pall
SKU: 43011
Price: 30000 GBP
Availability: InStock

Preço: £ 30.000

Pall Allegro 1/2" Single Use TFF System provides efficient tangential flow filtration for ultrafiltration and diafiltration in bioprocessing applications

Cambridgeshire, United Kingdom

A 5.773 km

Número do modelo

Allegro

Número de stock

43011

Machinery Masters View

Informação típica para esta categoria de máquinas. Confirme sempre os pormenores com o vendedor.

Concentration and purification of proteins, vaccines, and antibodies in biopharmaceutical manufacturing.
Diafiltration for buffer exchange and removal of small molecules from process streams.
Clarification of cell cultures and fermentation broths in upstream bioprocessing.
Pilot-scale and small-batch production where single-use technology minimises cross-contamination risk.

Typical membrane area: Units of this class commonly support membrane areas ranging from 0.05 m² to 0.5 m².
Flow path diameter: This specific unit features a 1/2" single-use flow path, suitable for various bioprocess volumes.
Power supply: Typically requires a standard laboratory power supply, often 230V, 50Hz for UK operation.
System footprint: For this class of benchtop system, the footprint is generally compact, suitable for laboratory or cleanroom environments.
Operating pressure range: Commonly operates within a pressure range suitable for ultrafiltration and diafiltration processes.
Materials in contact with fluid: Single-use components are typically constructed from validated biopharmaceutical-grade plastics.
Control interface: Often features an integrated control system for pump speed, pressure, and temperature monitoring.

Single-use bioprocess systems are valued for their flexibility, reduced contamination risk, and faster changeover between batches. Buyers appreciate the lower cleaning and validation requirements compared to reusable equipment. When purchasing used units, inspect for integrity of single-use components, verify sterility assurance levels, and confirm compatibility with existing infrastructure. Industry sentiment highlights their suitability for contract manufacturers and smaller facilities. Key considerations include supplier support availability and documentation of previous usage history to ensure reliability.

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Pall Allegro 1/2" Single Use TFF System

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