Akta PD - Akta Crossflow Filtration System

• Concentration of proteins, viruses, and nanoparticles in biotechnology.
• Diafiltration for buffer exchange and purification in pharmaceutical production.
• Clarification of cell cultures and fermentation broths.
• Pilot-scale and small-scale production in biopharmaceutical development.

Typical throughput

For this class of equipment, throughput can range from millilitres to several litres per hour, depending on membrane area and process parameters.

Membrane types

Units commonly support a variety of membrane types, including ultrafiltration and microfiltration, with various pore sizes.

Power supply

Typically operates on standard laboratory power supplies, commonly 230V, 50Hz in the UK.

Footprint

Benchtop or small cabinet design is common for units of this type, suitable for laboratory or pilot plant environments.

Materials of construction

Wetted parts are typically made from biocompatible materials such as stainless steel and various polymers to ensure product integrity.

Control system

Commonly features integrated control systems for flow rate, pressure, and temperature, often with automated process capabilities.

• What is crossflow filtration?

  Crossflow filtration, also known as tangential flow filtration (TFF), involves the feed solution flowing tangentially across the membrane surface, rather than perpendicularly. This minimises membrane fouling and allows for continuous operation.

• What are the main benefits of using an Akta Crossflow system?

• Can this system be used for different sample volumes?

• What kind of maintenance does a used unit typically require?

• Is this system suitable for GMP environments?

Separators and extraction systems are valued for their reliability in sample preparation workflows across laboratory and pharmaceutical settings. Buyers typically seek equipment with robust construction and minimal downtime history. Key considerations when purchasing used units include chamber integrity, seal condition, and calibration documentation. Industry sentiment favours models offering consistent reproducibility and easy maintenance. Established brands generally command confidence due to parts availability and technical support, though thorough inspection and performance testing remain essential before purchase.

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