Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration

• Used in biopharmaceutical production for concentrating proteins and other biomolecules.
• Applied in food and beverage processing for clarification and ingredient separation.
• Utilised in industrial biotechnology for enzyme recovery and purification.
• Employed in water treatment for removing suspended solids and macromolecules.

Typical flow rate

For this class of auxiliary pump, flow rates typically range from 0.5 to 10 litres per minute, depending on the specific application and membrane configuration.

Power supply

Units of this type commonly operate on standard single-phase industrial power, typically 230V, 50Hz in the UK.

Materials of construction

Wetted parts are typically constructed from biocompatible and chemically resistant materials such as 316L stainless steel and various polymers suitable for pharmaceutical and food contact.

Control interface

Commonly features integrated controls for flow and pressure, often with digital displays and connectivity for system integration.

Footprint

Auxiliary pumps for TFF systems are typically compact benchtop or skid-mounted units, designed to integrate with larger filtration setups.

Operating pressure range

These pumps typically operate within a pressure range suitable for ultrafiltration and diafiltration, commonly up to 5 bar.

• What is diafiltration?

  Diafiltration is a process used in tangential flow filtration (TFF) to efficiently remove small molecules, such as salts or solvents, from a solution containing larger molecules by continuously adding fresh buffer while removing permeate.

• Is this pump suitable for sterile applications?

• What maintenance is typically required for this type of pump?

• Can this pump be integrated with other TFF systems?

• What types of fluids can this pump handle?

Separators and extraction systems are valued for their reliability in sample preparation workflows across laboratory and pharmaceutical settings. Buyers typically seek equipment with robust construction and minimal downtime history. Key considerations when purchasing used units include chamber integrity, seal condition, and calibration documentation. Industry sentiment favours models offering consistent reproducibility and easy maintenance. Established brands generally command confidence due to parts availability and technical support, though thorough inspection and performance testing remain essential before purchase.

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