GE Axichrom - Axichrom 140/300 chromatography column

• Purification of proteins, peptides, and other biomolecules in biopharmaceutical production.
• Separation of target compounds from complex mixtures in research and development.
• Scale-up of chromatographic processes from laboratory to pilot and production scales.
• Polishing and impurity removal steps in downstream bioprocessing.
• Fractionation of natural products and other chemical compounds.

Column Diameter

This '140' model typically indicates a 140 mm internal diameter.

Column Length

The '300' in the model name commonly refers to a 300 mm bed height or column length.

Operating Pressure

For this class of equipment, it is designed for low-pressure axial compression chromatography.

Construction Material

Units of this type commonly feature wetted parts made from biocompatible materials such as stainless steel and inert polymers.

Packing Method

Designed to support automated column packing workflows for consistent bed quality.

Resin Compatibility

Typically compatible with a wide range of modern chromatography resins, including ion exchange, affinity, and size exclusion media.

• What is axial compression in chromatography columns?

  Axial compression involves applying pressure to the top of the packed bed, ensuring a uniformly compressed and stable bed. This method helps prevent void formation and improves separation efficiency and reproducibility.

• Why is automated column packing important?

• What kind of resins can be used with this column?

• Is this column suitable for GMP environments?

• What maintenance is typically required for such a column?

Chromatography columns and accessories hold strong reputations within analytical laboratories for reliability and consistent performance. Buyers typically value used equipment that maintains original specifications and comes with documentation of maintenance history. Industry sentiment favours purchasing from reputable sources where column condition, packing integrity, and compatibility with existing systems are verified. Common strengths include durability of quality columns across multiple applications and cost savings versus new purchases. When buying used, inspecting for damage, confirming proper storage conditions, and verifying suitability for intended analytical methods remain critical considerations for laboratory operations.

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