GE Healthcare UniFlux 120 TFF System

• Ultrafiltration and diafiltration in biopharmaceutical manufacturing.
• Concentration and purification of proteins, vaccines, and antibodies.
• Buffer exchange and desalting of biological solutions.
• Cell harvesting and clarification in cell culture processes.
• Pilot-scale and small-to-medium production in bioprocessing.

Typical capacity

For this class of equipment, it typically handles process volumes from several litres up to tens of litres, depending on membrane area.

Power supply

Commonly found on units of this type, a standard industrial electrical supply, often 230V, 50Hz, single-phase, is required.

Membrane compatibility

Typically compatible with a range of TFF cassettes from various manufacturers, offering flexibility in membrane pore size and material.

Control system

Units of this type commonly feature integrated control systems for automated operation, data logging, and process parameter monitoring.

Footprint

A compact design is typical for this model, suitable for laboratory or pilot plant environments where space may be limited.

Materials of construction

Wetted parts are typically constructed from biocompatible materials such as 316L stainless steel and USP Class VI polymers.

• What is Tangential Flow Filtration (TFF)?

  TFF is a filtration method where the feed stream flows tangentially across the surface of a membrane, rather than perpendicularly. This minimises membrane fouling and allows for continuous processing.

• What are the primary applications of a UniFlux 120 system?

• Can this system be integrated into existing bioprocessing lines?

• What kind of maintenance does a TFF system typically require?

• Is this system suitable for GMP environments?

Separators and extraction systems are valued for their reliability in sample preparation workflows across laboratory and pharmaceutical settings. Buyers typically seek equipment with robust construction and minimal downtime history. Key considerations when purchasing used units include chamber integrity, seal condition, and calibration documentation. Industry sentiment favours models offering consistent reproducibility and easy maintenance. Established brands generally command confidence due to parts availability and technical support, though thorough inspection and performance testing remain essential before purchase.

Vue d'ensemble pour ce type de machine