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Categoria do produto: Bioreactors & Fermenters
Bioreactors & Fermenters
The bioreactor is where a biomanufacturing process actually creates its product, and its control performance sets the ceiling on yield and consistency. Sellers in this collection list stirred-tank stainless bioreactors, single-use systems, and microbial fermenters from bench development scale through to production vessels of thousands of litres. You will find mammalian cell culture reactors, high-density microbial fermenters, and complete skids with control systems and instrumentation. Direct enquiries let you interrogate the important details, working volume, agitation, sterilisation method, and control platform, with the seller who ran the equipment.
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Applikon Pilot System 50L Fermentation system
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Bioreactors & Fermenters Product Types
Bioreactor design follows the organism and the scale, from delicate mammalian culture to vigorous microbial fermentation. These are the main types listed across the collection.
Stirred-Tank Stainless Bioreactors
Jacketed stainless vessels with mechanical agitation, SIP capability, and full instrumentation for temperature, pH, and dissolved oxygen. The established workhorse for both cell culture and fermentation at production scale.
Single-Use Bioreactors
Systems built around presterilised disposable bags in rocking or stirred formats, eliminating cleaning and sterilisation validation. Ideal for multi-product facilities and processes needing rapid campaign changeover.
Microbial Fermenters
Robust vessels designed for high cell densities, vigorous aeration, and the intensive CIP and SIP that bacterial and yeast processes demand. Higher power agitation and gas transfer distinguish them from cell culture reactors.
Benchtop and Pilot Bioreactors
Small autoclavable or single-use vessels from a few litres upward for process development, scale-down studies, and clone selection. Parallel bench systems let development teams run many conditions at once.
Photobioreactors
Illuminated tubular and flat-panel systems for culturing algae and photosynthetic organisms. Light path and mixing design govern productivity in these increasingly specified reactors.
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Cada vendedor é verificado antes de qualquer anúncio ser publicado. A Machinery Masters também revê a exatidão dos anúncios, para que os compradores possam investir com confiança em maquinaria de elevado valor.
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Contacto direto com o vendedor
Não há nenhum intermediário entre o comprador e o vendedor. Pergunte pelo histórico de manutenção, combine inspeções e negocie diretamente com a pessoa que realmente conhece a máquina.
Applications and Uses
Bioreactors serve every branch of biomanufacturing, but the vessel differs sharply with the organism and product. These four applications cover most of the demand seen in this collection.
Mammalian Cell Culture for Biologics
Stirred-tank reactors culture CHO and other cell lines to express monoclonal antibodies and recombinant proteins. Gentle agitation and precise dissolved oxygen control protect fragile cells over culture runs lasting many days.
Microbial Fermentation for Enzymes and Proteins
High-density bacterial and yeast fermentations produce industrial enzymes, biopharmaceuticals, and precision-fermented ingredients. These processes push oxygen transfer and cooling hard, so vessel and utility sizing must keep pace with metabolic heat.
Process Development and Scale-Up
Benchtop and pilot reactors let scientists define and de-risk conditions before committing to production. Reliable scale-down models are essential to predicting how a process behaves at manufacturing volume.
Cell and Gene Therapy Manufacturing
Single-use bioreactors suit the small, patient-specific batches and frequent changeovers these therapies require. Closed, disposable systems reduce contamination risk between separate patient products.
Benefits from Machinery Masters
Bioreactors and fermenters are among the most heavily specified assets in any facility, and sourcing them new or used through this marketplace works to the buyer's advantage.
01
Culture Vessels Across Every Scale
Bench, pilot, and production bioreactors in both stainless and single-use formats sit in one bioprocessing and pharmaceutical manufacturing collection, so a team can source development and production capacity for the same process from one set of listings.
02
Expensive Capacity at Realistic Cost
New production bioreactors carry substantial price tags and long build times, while used, decommissioned units listed here can shorten a project and preserve capital, with new options shown alongside for genuine comparison.
03
Control and History Straight from the Operator
Agitation performance, sterilisation method, and control system generation decide whether a bioreactor fits your process, and direct seller contact puts those questions to the people who ran the vessel.
Frequently Asked Questions sobre Bioreactors & Fermenters
Confirm the material certificates and internal surface finish, since product-contact requirements are strict for pharmaceutical use. Check the agitation system, seals, and sparger condition, and establish whether SIP capability is intact on stainless units. Review the control system generation and whether software and spares remain supported, because an obsolete controller can be the hidden cost that dwarfs the vessel. Ask for the vessel's process history and any surviving qualification documentation.
Stainless reactors give the lowest cost per batch at large scale and for long, single-product campaigns, but they need cleaning and sterilisation validation. Single-use systems remove that validation burden and suit multi-product suites and smaller batches, at a recurring consumable cost and a ceiling on practical scale. Base the decision on your batch size, number of products, and existing utility infrastructure rather than on the technology's novelty alone.
Distinguish total vessel volume from working volume, since a reactor is filled to perhaps 70 to 80 percent to leave headspace for foam and gassing. Size working volume from your required product mass and expected titre, and check the vessel's turndown, because one oversized for your smallest batch may not control pH or oxygen accurately at low fill. Sellers can confirm the rated minimum and maximum working volumes for their specific unit.
Oxygen transfer capability, often summarised as the vessel's mass transfer coefficient, limits how dense a microbial culture the fermenter can support. High cell density fermentations demand strong agitation and sparging, and a vessel built for gentle mammalian culture will not oxygenate a vigorous bacterial process. Match the reactor's aeration and agitation design to your organism, and ask the seller what processes and cell densities the vessel actually achieved in service.
Qualifying listings display a finance option, applied for from the listing page through the platform's lending partners while your technical evaluation continues. Bioreactors suit asset finance because they are durable, identifiable, and hold value across the industry. The seller relationship stays direct throughout, so decommissioning support, control system documentation, and spare parts can be negotiated into the same deal you are arranging to fund.