Applikon - BioPilot 70L Fermentation System

This listing is for 1 of 2 Applikon BioPilot 70L Fermenter.

The unit is in full working condition and is ready for immediate use

Overview

The Applikon BioPilot 70L is a fully integrated, pilot-scale fermentation system designed for microbial and cell culture applications in research, development, and small-scale production. Manufactured by Applikon Biotechnology, a global innovator in advanced bioreactor systems, the BioPilot 70L offers exceptional flexibility, process control, and scalability—bridging the gap between laboratory and production environments.

Key Features

Advanced Bioprocess Technology

Precision Control: Integrated control of key parameters such as pH, dissolved oxygen (DO), temperature, agitation, and feed rates.

Scalable Design: Built to mimic laboratory-scale conditions, enabling seamless scale-up to production volumes.

Modular Automation: Compatible with Applikon ez-Control, DeltaV, or Lucullus® PIMS for sophisticated process control and data management.

High-Quality Construction

70L Total Volume (50L Working Volume): Ideal for pilot studies, process optimization, and small-batch production.

316L Stainless Steel Vessel: Electro-polished and cGMP-compliant for pharmaceutical and biotechnological use.

Jacketed Design: Enables precise temperature control via thermal fluid circulation.

Technical Specifications

Model: BioPilot 70L

Total Volume: 70 liters

Working Volume: 50 liters (typical)

Vessel Material: 316L stainless steel, electro-polished

Control Options: ez-Control, DeltaV, Lucullus®

Sterilization: In-situ sterilizable (SIP) and Clean-in-Place (CIP) compatible

Ports: Multiple ports for probes, additions, sampling, gas inlets/outlets

Applications

Biopharmaceuticals: Production of recombinant proteins, enzymes, vaccines

Industrial Biotechnology: Fermentation of bio-based chemicals and specialty metabolites

Food & Beverage: Cultivation of probiotics and functional ingredients

Academic & R&D: Process development, scale-up studies, and microbial strain screening

System Components

70L stainless steel fermentation vessel (jacketed)

Modular control tower or integrated skid system

Peristaltic pumps for acid/base, antifoam, and nutrient feed

Autoclavable or SIP-compatible sensors for pH, DO, temperature, and level

Gas flow control via mass flow controllers (MFCs) or rotameters

Harvest and sampling ports, exhaust condenser, and sterile connections

Quality Assurance

Applikon fermentation systems are engineered and manufactured under strict quality control standards, ensuring full cGMP and FDA compliance where required. Factory Acceptance Testing (FAT), documentation, and validation support are provided for regulated environments.

Benefits

Flexible Configuration: Customizable to meet process-specific requirements

Reliable Scale-Up: Accurate replication of lab-scale conditions in pilot volumes

High-Level Automation: Advanced monitoring and control systems for optimized yields

Ease of Integration: Compatible with existing bioprocess infrastructure

Compliance-Ready: Suited for regulated production and research environments

Conclusion

The Applikon BioPilot 70L Fermentation System is the perfect solution for companies and institutions needing a reliable, scalable, and compliant bioreactor platform. With precise control, robust construction, and full integration capability, it empowers bioprocess development from the lab bench to commercial readiness.