Applikon Pilot System 50L Fermentation system

• Pilot-scale production of biopharmaceuticals, vaccines, and enzymes.
• Development and optimisation of fermentation processes for various microorganisms.
• Small-batch production of food ingredients, probiotics, and industrial chemicals.
• Research and development in biotechnology, microbiology, and biochemical engineering.

Typical capacity

For a pilot system of this type, the working volume is commonly around 50 litres.

Construction material

Units like this are typically constructed from stainless steel (e.g., 316L) for sterility and corrosion resistance.

Power supply

Pilot-scale fermenters commonly require a 3-phase industrial power supply, typically 400V AC in the UK.

Temperature control

Integrated heating and cooling jackets are standard for precise temperature regulation.

Agitation system

These systems typically feature mechanical agitation with impellers suitable for various cell cultures.

Instrumentation

Commonly includes sensors for pH, dissolved oxygen, temperature, and foam detection.

Sterilisation method

Units of this class are typically sterilised in place (SIP) using steam.

• What is the typical footprint of a 50L pilot fermentation system?

  The footprint can vary, but buyers should expect a system requiring approximately 1.5m x 1.5m of floor space, plus clearance for maintenance and utility connections.

• What utilities are required to operate this type of system?

• Is this system suitable for both microbial and cell culture applications?

• What level of automation can be expected?

• What maintenance is typically involved with a used fermentation system?

Bioreactors and fermenters are valued for reliable performance in scaling bioprocess development and manufacturing. Buyers typically prioritise vessel integrity, sterilisation capability, and control system functionality when purchasing used equipment. Industry sentiment favours units with documented maintenance histories and calibrated instrumentation. Key strengths include robust construction and adaptability across multiple applications. Common considerations include sensor condition, heating and aeration systems, and compatibility with existing facility infrastructure. Equipment from established manufacturers generally commands buyer confidence for critical bioprocessing operations.

General overview for this equipment type