Product category: Homogenizers & Sonicators
used Equipment
Available
Avestin - EmulsiFlex-C5 For Homogenizer With Sealed Toolings And Spares
This listing is for the Avestin EmulsiFlex-C5 for homogenizer with sealed toolings and spares
The unit is in full working condition and is ready for immediate use
EmulsiFlex-C5 High Pressure Homogenizer
The Avestin EmulsiFlex-C5 is a high-pressure, pneumatically powered homogenizer designed for laboratory-scale applications. It is ideal for processing small to medium sample volumes, from 7 mL up to 5 L/h, depending on the pressure applied.
How It Works: High Pressure Homogenisation
High pressure homogenisation is an efficient and easy-to-use technique for cell disruption and liposome/emulsion processing.
The principle involves pumping the sample through a valve with a small aperture. The sample transitions from very high pressure (up to 30,000 psi) on the pump side to atmospheric pressure on the outlet side. This sudden drop in pressure creates intense shear forces, disrupting cell membranes or dramatically reducing liposome/emulsion sizes.
For cells, the pressure-induced shear forces rupture the membranes, effectively lysing the cells.
For liposomes and emulsions, this process reduces their size from micron to nanometer range, often resulting in uniform particles with narrow size distributions.
Unique Features of the EmulsiFlex-C5
Dynamic Homogenising Valve
The C5 uses a dynamic homogenising valve, which maintains constant pressure during sample processing. This consistency ensures the formation of highly uniform liposomes and micro-emulsions, with tight particle size distributions.
Efficient Cell Disruption
Most cells (including E. coli) can be lysed in a single pass, minimizing over-processing and reducing the risk of protein denaturation or degradation.
Pressure Range: Adjustable from 500 to 30,000 psi
Flow Rate: 1–5 L/h depending on pressure
Minimum Sample Volume: 7 mL
Holdback Volume: Less than 1 mL
Temperature Control: Can be used with ice baths, external chillers, or in cold rooms
Autoclavable: Easy cleaning and sterilization (SIP-compatible)
Compact Size: 430 × 160 × 320 mm, 25 kg
Power Source: Requires compressed or bottled air. For most applications (e.g., E. coli disruption or liposome formation), 100 psi air pressure is sufficient.
Applications
Disruption of bacterial, yeast, algal, insect, or mammalian cells
Nano-sized liposome and emulsion formation
Particle size reduction in pharmaceuticals, cosmetics, and food products
Liposomal drug delivery systems
Efficient homogenisation for biochemical and biophysical research
5,791 km away
Model Number
EmulsiFlex-C5
Stock Number
ANT.AV.SR9B
Machinery Masters View
Typical context for this category of equipment. Always confirm specifics with the seller.
Applications & Use Cases
- Cell disruption for protein extraction or vaccine production.
- Liposome and nanoparticle formulation for drug delivery systems.
- Emulsion and micro-emulsion creation for food, cosmetic, and pharmaceutical products.
- Particle size reduction in suspensions for improved stability and bioavailability.
Typical Specifications
- Typical throughput
- For this class of equipment, throughput commonly ranges from 7 mL up to 5 L/h, depending on the operating pressure.
- Operating pressure
- Units of this type typically operate at high pressures, up to 30,000 psi (2070 bar).
- Power supply
- Pneumatically powered homogenizers commonly require a compressed air supply, often 6-8 bar.
- Sample volume
- Suitable for laboratory-scale processing of small to medium sample volumes.
- Homogenising valve
- Often features a dynamic homogenising valve for consistent pressure and uniform particle size distribution.
- Footprint
- Laboratory-scale units are typically compact, designed for benchtop use.
Frequently Asked Questions
- High-pressure homogenisation involves forcing a sample through a narrow valve at high pressure, causing a sudden pressure drop. This creates intense shear forces that disrupt cells or reduce particle sizes in emulsions and liposomes.
Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.