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by Grant CRF-1 Controlled Rate Freezer is a used laboratory freezers listing available for GBP 5000. Browse specifications, request seller details, and find similar equipment on Machinery Masters.
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Grant CRF-1 Controlled Rate Freezer -
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Price: £ 5,000
This listing is for a Grant Controlled Rate Freezer - CRF-1
The unit is in full working condition and is ready for immediate release
Product Overview:
The CRF-1 Liquid Nitrogen-Free Controlled Rate Freezer is designed for precision-controlled freezing and cryopreservation of biological samples, such as embryos, stem cells, mammalian cells, spermatozoa, antibodies, tissue sections, and rodent organs. Unlike conventional liquid nitrogen-based freezers, the CRF-1 is liquid nitrogen and cryogen-free, eliminating contamination risks and making it suitable for use in cleanrooms and barrier facilities. It offers superior performance in terms of cell viability post-freezing and poses no fire hazard, unlike alcohol-based systems.
The CRF-1 allows for highly accurate, reproducible, and controlled freezing rates, crucial for the cryopreservation of biological samples, ensuring optimal recovery upon thawing.
Key Features:
Cryogen-Free Design: The CRF-1 is free from liquid nitrogen and alcohol, offering a safer, cleaner alternative to traditional freezing methods. No contamination risk, making it ideal for use in sterile environments.
Precise Cooling Control: The cooling rate is accurately controlled, especially for the critical nucleation/seeding phase, which ensures consistent and optimal recovery of cells.
Wide Temperature Range: Capable of cooling down to -100°C with straws, offering a broad application range for biological cryopreservation.
Simple Operation: The CRF-1 operates with or without a PC, and it can log data via PC software. Cooling profiles are displayed directly and can be customized.
High Versatility: Compatible with cryovials, straws, bags, microplates, and Matrix-96-well block plates, allowing for research across multiple areas like stem cell research, transgenic embryos, mammalian cells, and more.
Low Operational Costs: The CRF-1 runs at approximately 1% of the cost of liquid nitrogen-based freezing systems.
Safety Features: Includes an optional Un-interruptible Power Supply (UPS) for complete cycle continuation in case of power failure.
Compact & Quiet: Fits neatly on a bench-top and operates quietly, making it suitable for laboratory settings.
Main Applications:
Transgenic embryos research
Stem cell research
Clinical and research samples like lymphocytes and tissue cell lines
Mammalian cell preservation (e.g., cardiomyocytes, adipose, liver, muscle)
Cord blood-derived stem cells
Adherent cells and stem cells in microplates
Cell suspensions in numbered/barcoded arrays
Robotic integration for high-throughput applications
Veterinarian IVF applications
Technical Specifications:
Dimensions (w x d x h): 264 x 367 x 445 mm
Weight: 9.8 kg
Max Plate Temperature: 30°C
Min Plate Temperature: -80°C (standard) or -100°C (dependent on model)
Temperature Accuracy: ±0.5°C
Temperature Stability: ±0.1°C
Temperature Uniformity: ±1.0°C
Max Cooling Rate: 10°C/min
Max Temperature Stabilization Time: 5 minutes
Key Benefits:
Accurate and Reproducible Cooling Rates: Ensures controlled freezing rates and precise sample temperature management.
Customizable Cooling Profiles: Choose from linear and non-linear profiles, or create your own tailored profile.
No Cryogen or Liquid Nitrogen: Ideal for reducing contamination risk and the cost of liquid nitrogen.
Low Running Costs: Estimated to cost only 1% of traditional liquid nitrogen-controlled freezing methods.
End-of-Cycle Cooling Stability: Maintains a steady -100°C temperature for straw applications until the freezer is switched off.
CE Marked: For laboratory use in compliance with safety and quality standards.
The unit is in full working condition and is ready for immediate release
Cambridgeshire, United Kingdom5,791 km away
Model Number
CRF-1 Controlled Rate Freezer
Stock Number
51136
Machinery Masters View
Typical context for this category of equipment. Always confirm specifics with the seller.
Applications & Use Cases
- Cryopreservation of biological samples in research laboratories.
- Storage of embryos, stem cells, and mammalian cells in biotech facilities.
- Preservation of spermatozoa and antibodies for pharmaceutical development.
- Freezing of tissue sections and rodent organs for pathology and toxicology studies.
- Use in cleanroom environments where liquid nitrogen contamination is a concern.
Typical Specifications
- Temperature Range
- Typically capable of cooling down to -100°C for this class of equipment.
- Cooling Method
- Cryogen-free, utilising advanced refrigeration technology rather than liquid nitrogen or alcohol.
- Cooling Rate Control
- Units of this type commonly offer precise and reproducible control over cooling rates, particularly during the nucleation phase.
- Sample Formats
- Typically accommodates various biological sample formats, such as straws, vials, and cryobags.
- Power Supply
- Commonly operates on standard laboratory single-phase power, typically 230V, 50Hz for the UK market.
- Footprint
- For this class of laboratory equipment, units are typically designed to be benchtop or compact floor-standing.
Frequently Asked Questions
- Cryogen-free systems eliminate the need for liquid nitrogen or alcohol, reducing contamination risks, fire hazards, and ongoing consumable costs. They are also suitable for use in cleanroom environments.
Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.