Grant CRF-1 Controlled Rate Freezer -

This listing is for a Grant Controlled Rate Freezer - CRF-1

The unit is in full working condition and is ready for immediate release

Product Overview:

The CRF-1 Liquid Nitrogen-Free Controlled Rate Freezer is designed for precision-controlled freezing and cryopreservation of biological samples, such as embryos, stem cells, mammalian cells, spermatozoa, antibodies, tissue sections, and rodent organs. Unlike conventional liquid nitrogen-based freezers, the CRF-1 is liquid nitrogen and cryogen-free, eliminating contamination risks and making it suitable for use in cleanrooms and barrier facilities. It offers superior performance in terms of cell viability post-freezing and poses no fire hazard, unlike alcohol-based systems.

The CRF-1 allows for highly accurate, reproducible, and controlled freezing rates, crucial for the cryopreservation of biological samples, ensuring optimal recovery upon thawing.

Key Features:

Cryogen-Free Design: The CRF-1 is free from liquid nitrogen and alcohol, offering a safer, cleaner alternative to traditional freezing methods. No contamination risk, making it ideal for use in sterile environments.

Precise Cooling Control: The cooling rate is accurately controlled, especially for the critical nucleation/seeding phase, which ensures consistent and optimal recovery of cells.

Wide Temperature Range: Capable of cooling down to -100°C with straws, offering a broad application range for biological cryopreservation.

Simple Operation: The CRF-1 operates with or without a PC, and it can log data via PC software. Cooling profiles are displayed directly and can be customized.

High Versatility: Compatible with cryovials, straws, bags, microplates, and Matrix-96-well block plates, allowing for research across multiple areas like stem cell research, transgenic embryos, mammalian cells, and more.

Low Operational Costs: The CRF-1 runs at approximately 1% of the cost of liquid nitrogen-based freezing systems.

Safety Features: Includes an optional Un-interruptible Power Supply (UPS) for complete cycle continuation in case of power failure.

Compact & Quiet: Fits neatly on a bench-top and operates quietly, making it suitable for laboratory settings.

Main Applications:

Transgenic embryos research

Stem cell research

Clinical and research samples like lymphocytes and tissue cell lines

Mammalian cell preservation (e.g., cardiomyocytes, adipose, liver, muscle)

Cord blood-derived stem cells

Adherent cells and stem cells in microplates

Cell suspensions in numbered/barcoded arrays

Robotic integration for high-throughput applications

Veterinarian IVF applications

Technical Specifications:

Dimensions (w x d x h): 264 x 367 x 445 mm

Weight: 9.8 kg

Max Plate Temperature: 30°C

Min Plate Temperature: -80°C (standard) or -100°C (dependent on model)

Temperature Accuracy: ±0.5°C

Temperature Stability: ±0.1°C

Temperature Uniformity: ±1.0°C

Max Cooling Rate: 10°C/min

Max Temperature Stabilization Time: 5 minutes

Key Benefits:

Accurate and Reproducible Cooling Rates: Ensures controlled freezing rates and precise sample temperature management.

Customizable Cooling Profiles: Choose from linear and non-linear profiles, or create your own tailored profile.

No Cryogen or Liquid Nitrogen: Ideal for reducing contamination risk and the cost of liquid nitrogen.

Low Running Costs: Estimated to cost only 1% of traditional liquid nitrogen-controlled freezing methods.

End-of-Cycle Cooling Stability: Maintains a steady -100°C temperature for straw applications until the freezer is switched off.

CE Marked: For laboratory use in compliance with safety and quality standards.

The unit is in full working condition and is ready for immediate release