Halo - Halo Labs Horizon Particle Analyzer

Applications & Use Cases

• Characterising subvisible particles in biopharmaceutical formulations, particularly protein aggregates.
• Quality control and lot release testing in pharmaceutical manufacturing.
• Research and development for new drug formulations and stability studies.
• Analysis of particulate contamination in various liquid samples.
• Evaluating particle size distribution in academic and industrial laboratory settings.

Typical Specifications

Typical throughput

Units of this type commonly process up to 96 samples per run.

Sample volume

Typically requires a low sample volume, often around 25 µL per sample.

Measurement technology

This class of equipment utilises Backgrounded Membrane Imaging (BMI) technology.

Particle size range

Designed for subvisible particle analysis, typically covering a range relevant to protein aggregates.

Power supply

Commonly operates on standard laboratory power, typically 100-240V AC, 50/60Hz.

Operational footprint

For this class of analytical instrument, a dedicated benchtop space is typically required.

Frequently Asked Questions

• What is Backgrounded Membrane Imaging (BMI) technology?

  BMI is an imaging method where particles are filtered onto a membrane. A background image of the clean membrane is taken, followed by an image of the membrane with particles. Sophisticated image processing then removes the background texture to accurately count and size the particles.

• Is this system suitable for analysing translucent protein aggregates?

• What kind of consumables does this system use?

• Does this unit require a dedicated PC and monitor?

• What are the typical maintenance requirements for a particle analyzer of this type?