What is Backgrounded Membrane Imaging (BMI) technology?

BMI technology images particles on a membrane surface after filtration. It captures a background image of the membrane, filters the sample, then re-images the membrane with particles. Sophisticated image processing removes background texture for high-contrast particle analysis.

What types of particles can this system analyse?

This system is specifically designed for accurately measuring and characterising subvisible particles, including translucent protein aggregates, which is critical in biopharmaceutical applications.

Is a PC/Monitor included with the unit?

This particular listing states that a PC/Monitor is not included. Buyers should factor this into their setup requirements.

What are the typical benefits of a fluidics-free system?

A fluidics-free system typically reduces cross-contamination risks, simplifies maintenance, and often improves reliability by eliminating complex tubing and pumps associated with traditional fluidic pathways.

How does this system ensure accurate measurement of translucent protein aggregates?

The BMI technology is designed to be unaffected by solution refractive index. This ensures accurate measurement of translucent protein aggregates, which can be challenging for other particle analysis methods.

What level of reproducibility can be expected?

The imaging approach, with its meticulous alignment and pixel-by-pixel processing to remove background texture, is designed to yield high reproducibility and minimise interference from membrane texture or imperfections.

Home
/
Labs, Biotech & Pharma
/
Analytical Instruments & Detection Systems
/
Particle Counters & Particle Analysis Systems
/
Halo Labs Horizon Particle Analyzer

Used Halo Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 1

Used Halo Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 2

Used Halo Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 3

Used Halo Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 4

Used Halo Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 5

Used Halo Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 6

Used Halo Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems

used Equipment

Available

Verified seller

Halo Labs Horizon Particle Analyzer

Name: Halo Labs Horizon Particle Analyzer
Brand: Halo
SKU: 55672.SR8C
Availability: InStock

Price: Contact seller for price

This listing is for a Halo Labs Horizon Particle Analyzer.

The unit is in full working condition and is ready for immediate release.

No PC/Monitor.

The Horizon system from Halo Labs integrates Backgrounded Membrane Imaging (BMI) technology to accurately measure and characterize subvisible particles in a high-throughput, low-volume format.

Originating from membrane microscopy, a USP lot release method, BMI images particles on a membrane surface.

This fully automated, fluidics-free Horizon system employs disposable membrane plates and automated image processing for quick, reliable particle counts and sizing.

Capable of characterizing particles in up to 96 samples per run using only 25 µL per sample, BMI is unaffected by solution refractive index, ensuring accurate measurement of translucent protein aggregates.

Sophisticated image processing techniques are used to analyze and acquire particle data, beginning with a background image of the membrane.

After filtering samples by vacuum and capturing particles, the membrane is re-imaged with sample particles on its surface.

The sample image is meticulously aligned with the background and processed pixel by pixel to remove background texture, achieving high contrast for the particles.

This imaging approach yields high reproducibility and minimizes interference from membrane texture or imperfections.

Key Features:

Backgrounded Membrane Imaging (BMI) technology for precise particle measurement.
High-throughput: Capable of analyzing up to 96 samples in a single run.
Low sample volume: Requires only 25 µL per sample.
Fully automated, fluidics-free system for seamless operation.
Accurate measurement of translucent protein aggregates, unaffected by solution refractive index.
Sophisticated image processing for high reproducibility and minimal interference.

Cambridgeshire, United Kingdom

5,773 km away

Model Number

Horizon

Stock Number

55672.SR8C

Machinery Masters View

Typical context for this category of equipment. Always confirm specifics with the seller.

Quality control and R&D in biopharmaceutical development for protein aggregation analysis.
Characterisation of subvisible particles in injectable drug products.
Analysis of particulate contamination in various liquid samples.
Formulation development and stability testing for biologics.

Measurement Technology: Backgrounded Membrane Imaging (BMI) for precise particle measurement.
Sample Throughput: Typically high-throughput, commonly found with capabilities for up to 96 samples per run.
Sample Volume: Low sample volume requirement, typically around 25 µL per sample for this class of equipment.
Particle Size Range: Designed for subvisible particles, with specific ranges varying by model but generally covering critical pharmaceutical particle sizes.
Interference: BMI technology is typically unaffected by solution refractive index.
Automation: Fully automated fluidics-free system, common for advanced particle analyzers.
Consumables: Utilises disposable membrane plates.
Power Supply: Commonly operates on standard laboratory power supplies, typically 100-240V AC.

BMI technology images particles on a membrane surface after filtration. It captures a background image of the membrane, filters the sample, then re-images the membrane with particles. Sophisticated image processing removes background texture for high-contrast particle analysis.

Particle counters and analysis systems are regarded as essential tools for quality assurance and contamination control across pharmaceutical, biotech and food processing sectors. When purchasing used units, buyers should verify calibration history and optical component condition, as these directly affect measurement accuracy. Industry users value their reliability and precision for meeting regulatory compliance standards. Key strengths include consistent performance across batch testing and minimal maintenance requirements when properly maintained.

General overview for this equipment type

Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.