What is Backgrounded Membrane Imaging (BMI) technology?

BMI is an imaging method where particles are filtered onto a membrane. A background image of the clean membrane is taken, followed by an image of the membrane with particles. Sophisticated image processing then removes the background texture to accurately count and size the particles.

Is this system suitable for analysing translucent protein aggregates?

Yes, the BMI technology used in these systems is typically unaffected by solution refractive index, making it suitable for accurate measurement of translucent protein aggregates.

What kind of consumables does this system use?

Units of this type commonly employ disposable membrane plates for sample processing, ensuring consistency and reducing cross-contamination.

Does this unit require a dedicated PC and monitor?

Yes, while the analyser itself is a standalone unit, a separate PC and monitor are typically required to run the control software and display results. These are not usually included with the analyser unit itself.

What are the typical maintenance requirements for a particle analyzer of this type?

Maintenance typically involves routine cleaning of the fluidics path (if applicable) and optical components, along with periodic calibration checks. The use of disposable consumables minimises direct contact with samples, simplifying cleaning procedures.

Used Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 1

Used Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 2

Used Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 3

Used Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 4

Used Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 5

Used Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems, photo 6

Used Labs Horizon Particle Analyzer - Particle Counters & Particle Analysis Systems

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Available

Verified seller

Halo - Labs Horizon Particle Analyzer

Name: Labs Horizon Particle Analyzer
Brand: Halo
SKU: 55672.SR8C
Availability: InStock

Price: Contact seller for price

This listing is for a Halo Labs Horizon Particle Analyzer

The unit is in full working condition and is ready for immediate release

(No PC/Monitor)

The Horizon system from Halo Labs integrates Backgrounded Membrane Imaging (BMI) technology to accurately measure and characterize subvisible particles in a high-throughput, low-volume format. Originating from membrane microscopy, a USP lot release method, BMI images particles on a membrane surface. This fully automated, fluidics-free Horizon system employs disposable membrane plates and automated image processing for quick, reliable particle counts and sizing. Capable of characterizing particles in up to 96 samples per run using only 25 µL per sample, BMI is unaffected by solution refractive index, ensuring accurate measurement of translucent protein aggregates.

Sophisticated image processing techniques are used to analyze and acquire particle data, beginning with a background image of the membrane. After filtering samples by vacuum and capturing particles, the membrane is re-imaged with sample particles on its surface. The sample image is meticulously aligned with the background and processed pixel by pixel to remove background texture, achieving high contrast for the particles. This imaging approach yields high reproducibility and minimizes interference from membrane texture or imperfections.

Key Features:

Backgrounded Membrane Imaging (BMI) technology for precise particle measurement.

High-throughput: Capable of analyzing up to 96 samples in a single run.

Low sample volume: Requires only 25 µL per sample.

Fully automated, fluidics-free system for seamless operation.

Accurate measurement of translucent protein aggregates, unaffected by solution refractive index.

Sophisticated image processing for high reproducibility and minimal interference.

Cambridgeshire, United Kingdom

5,791 km away

Model Number

Horizon

Stock Number

55672.SR8C

Machinery Masters View

Typical context for this category of equipment. Always confirm specifics with the seller.

Applications & Use Cases

Characterising subvisible particles in biopharmaceutical formulations, particularly protein aggregates.
Quality control and lot release testing in pharmaceutical manufacturing.
Research and development for new drug formulations and stability studies.
Analysis of particulate contamination in various liquid samples.
Evaluating particle size distribution in academic and industrial laboratory settings.

Typical Specifications

Typical throughput: Units of this type commonly process up to 96 samples per run.
Sample volume: Typically requires a low sample volume, often around 25 µL per sample.
Measurement technology: This class of equipment utilises Backgrounded Membrane Imaging (BMI) technology.
Particle size range: Designed for subvisible particle analysis, typically covering a range relevant to protein aggregates.
Power supply: Commonly operates on standard laboratory power, typically 100-240V AC, 50/60Hz.
Operational footprint: For this class of analytical instrument, a dedicated benchtop space is typically required.

Frequently Asked Questions

BMI is an imaging method where particles are filtered onto a membrane. A background image of the clean membrane is taken, followed by an image of the membrane with particles. Sophisticated image processing then removes the background texture to accurately count and size the particles.

Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.