Leica Reichert MM80 E Mirror Cryo Fixation Unit

• Rapid freezing of biological samples for electron microscopy.
• Preservation of tissue morphology for ultrastructural analysis.
• Preparation of samples for immunocytochemistry.
• Research in cell biology and neuroscience.
• Material science applications requiring rapid cooling.

Typical sample size

Units of this type are designed for very small biological samples, often in the sub-millimetre range.

Cooling method

Mirror cryo fixation units typically employ a highly polished copper mirror cooled by liquid nitrogen or helium for ultra-rapid freezing.

Freezing rate

This class of equipment is known for achieving extremely high freezing rates, often thousands of degrees Celsius per second, to minimise ice crystal formation.

Operating temperature

The mirror surface commonly operates at temperatures well below -190°C.

Power supply

Typically requires a standard laboratory single-phase electrical supply, such as 230V, 50Hz for UK operation.

Footprint

Benchtop units, commonly requiring a dedicated space of approximately 40-60 cm in width and depth.

Consumables

Requires a supply of liquid nitrogen or helium, depending on the specific model's cooling system.

• What is mirror cryo fixation?

  Mirror cryo fixation is a technique that uses a highly polished, super-cooled metal mirror to rapidly freeze biological samples, preserving their ultrastructure by preventing the formation of large ice crystals.

• Why is rapid freezing important for biological samples?

• What maintenance is typically required for a unit like this?

• Can this unit be used for all types of biological samples?

• Are specific safety precautions needed when operating a cryo fixation unit?

Cryo fixation units are valued in laboratories for preserving specimen integrity during processing. Buyers typically seek models offering reliable temperature control and rapid freezing capabilities. Used units warrant inspection of cooling systems, thermal consistency, and maintenance history, as performance degradation directly affects sample quality. Industry users appreciate equipment delivering uniform preservation results whilst minimising ice crystal formation. Key considerations include chamber capacity, defrost mechanisms, and compatibility with existing laboratory workflows. Established manufacturers generally command confidence amongst purchasers seeking dependable performance.

General overview for this equipment type