Malvern Archimedes Particle Metrology plus PC

• Characterisation of protein aggregates in pharmaceutical formulations and buffers.
• Detection and quantification of sub-micron particles in biological samples.
• Differentiation between proteinaceous material and contaminants like silicone oil.
• Quality control in biopharmaceutical development and manufacturing.
• Research and development involving nanoparticle analysis and characterisation.

Particle Size Range

Typically 50nm to 5µm for this class of equipment.

Measurement Principle

Commonly resonant mass measurement (RMM) for high-precision particle analysis.

Measured Parameters

Typically buoyant mass, dry mass, and particle size.

Sample Volume

Units of this type often require small sample volumes, typically in the microlitre range.

Throughput

Analysis times can vary, but single sample analysis is generally rapid for this technology.

Power Supply

Typically standard laboratory mains power (e.g., 230V, 50Hz in the UK) with low power consumption.

Connectivity

Commonly includes USB or Ethernet for PC connection and data transfer.

• What is resonant mass measurement (RMM)?

  RMM is a technique that measures the change in resonant frequency of a micro-cantilever as a particle passes through it. This allows for precise determination of particle mass and size.

• Can this system differentiate between different types of particles?

• Is specialist training required to operate this equipment?

• What kind of maintenance does a particle metrology system require?

• What software is typically used with these systems?

Particle counters and analysis systems are regarded as essential tools for quality assurance and contamination control across pharmaceutical, biotech and food processing sectors. When purchasing used units, buyers should verify calibration history and optical component condition, as these directly affect measurement accuracy. Industry users value their reliability and precision for meeting regulatory compliance standards. Key strengths include consistent performance across batch testing and minimal maintenance requirements when properly maintained.

General overview for this equipment type