Spectrum Labs - Spectrum Labs Krosflo 11 Automatic Backpressure Valve

Applications & Use Cases

• Concentration and diafiltration of proteins, viruses, and nanoparticles.
• Clarification of cell cultures and fermentation broths.
• Buffer exchange and desalting of biological samples.
• Fractionation of complex mixtures in research and development settings.

Typical Specifications

Typical processing volume

For this class of system, processing volumes commonly range from 2 mL to 15 L.

Filtration type

Units of this type are designed for microfiltration and ultrafiltration applications.

Power supply

Typically, laboratory-scale systems like this operate on standard single-phase mains power, commonly 230V, 50Hz in the UK.

Control

Systems in this category often feature integrated pumps and pressure sensors for automated control of filtration parameters.

Membrane compatibility

These systems are generally compatible with a range of flat sheet or hollow fibre TFF membranes, allowing for diverse application use.

Footprint

Laboratory TFF systems typically have a compact benchtop footprint, suitable for standard lab environments.

Frequently Asked Questions

• What is the primary function of a TFF system like the KrosFlo Research II?

  The primary function is to separate, purify, and concentrate biomolecules and particles in liquid solutions using tangential flow filtration membranes.

• What types of membranes can be used with this system?

• Is this system suitable for pilot-scale production?

• What maintenance is typically required for a TFF system?

• Can this system handle viscous fluids?