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Product category: Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC)
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Vanquish UHPLC System by Thermo Scientific is a used chromatography systems (hplc, uhplc, gc, lcms, gpc-sec) listing available for GBP 38000. Browse specifications, request seller details, and find similar equipment on Machinery Masters.
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Thermo Scientific - Vanquish UHPLC System
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Price: £ 38,000
This listing is for the Thermo Scientific Vanquish UHPLC Sytem
The unit is in full working condition and is ready for immediate use
Overview: Thermo Scientific Vanquish UHPLC Systems
1. Autosampler
Purpose: Introduces the sample into the mobile phase stream automatically.
Picks up sample from vials, plates, or tubes
Injects with high precision (often nL to µL volume range
Module
Purpose: Delivers the mobile phase (solvent) through the system at high pressure.
Binary pump: Mixes two solvents at high pressure. Ideal for fast gradients.
Quaternary pump: Mixes up to four solvents at low pressure. More flexible, but slower gradients.
Controls flow rate (e.g., 0.001–5.000 mL/min)
Enables gradient elution (changing solvent composition over time
Module (x2)
Purpose: Detects and measures analytes as they elute from the column.
Diode Array Detector (DAD/UV-Vis) – most common; detects UV-absorbing compounds
Fluorescence Detector – for fluorescent compounds
Charged Aerosol Detector (CAD) – universal detection for non-UV compounds
Refractive Index Detector – for sugars, polymers
MS (Mass Spectrometer) – advanced, highly sensitive detection
Thermo Fisher’s Vanquish platform includes several variants tailored to different analytical needs—from routine HPLC to ultra-high-throughput and low-flow LC–MS workflows:
Vanquish Flex UHPLC: Offers flexible HPLC/UHPLC method development and operates up to 1000 bar. It supports binary, quaternary, and dual pumps, plus intelligent tools like solvent monitoring and optional touchscreen interface.
Vanquish Horizon UHPLC: Built for maximum performance, offering ultra-high pressure (up to 1500 bar), ultra-low gradient delay volume, biocompatible flow paths, and exceptional retention time stability and detector sensitivity.
Vanquish Neo UHPLC: Designed for next-gen low-flow LC‑MS workflows (nano‑ to micro‑flow), delivering high‑sensitivity, high‑robustness separations.
Vanquish Analytical Purification LC: Specialized for precise fractionation—high pressure (700–1500 bar), customizable flow (up to 10 mL/min), integrated fraction collector, multimodal detection, and advanced automation.
Key Features Across the Platform
Modular Design: Choose components (pumps, samplers, detectors, thermostatting units) to configure a tailored system. Most models offer biocompatible flow paths and Viper fingertight fittings for low dead‑volume, tool‑free setup.
Temperature Control: High-performance column compartments with active/passive heating, pre‑heating, and post‑column cooling to manage frictional heating and improve reproducibility.
Detection Options: Available detectors include Diode Array (with LightPipe optics for superb sensitivity), Charged Aerosol Detector (CAD) for near‑universal detection, fluorescence, multi‑wavelength, refractive index, and mass spectrometry detection.
Software Integration: Fully compatible with Chromeleon CDS (with SII for streamlined MS integration), plus Xcalibur and TraceFinder for LC‑MS workflows.
MS Integration: Vanquish systems interface seamlessly with Thermo MS platforms—Triple Quadrupole and Orbitrap—for sensitive, accurate mass analysis.
Operational ROI: Thermo highlights reduced unplanned repairs, improved productivity, and net-zero ambitions through renewable-powered manufacturing.
Cambridgeshire, United Kingdom5,791 km away
Model Number
Vanquish
Stock Number
49364.1535.17A
Machinery Masters View
Typical context for this category of equipment. Always confirm specifics with the seller.
Applications & Use Cases
- Pharmaceutical research and quality control for drug discovery and impurity profiling.
- Biotechnology for protein and peptide analysis, and biomolecule characterisation.
- Environmental testing for contaminant analysis in water, soil, and air samples.
- Food and beverage industry for nutrient analysis, additive detection, and authenticity testing.
- Chemical and petrochemical industries for polymer analysis and process monitoring.
Typical Specifications
- Operating Pressure
- Typically up to 1000-1500 bar (15,000-22,000 psi) for UHPLC systems, enabling faster separations and higher resolution.
- Flow Rate Range
- Commonly 0.001 to 5.000 mL/min, with high precision for various column dimensions.
- Autosampler Capacity
- Often accommodates multiple plates (e.g., 2-4 microtiter plates) or hundreds of vials, depending on the configuration.
- Detector Types
- Units of this type commonly integrate with Diode Array (DAD), UV-Vis, Fluorescence, Charged Aerosol (CAD), Refractive Index (RI), or Mass Spectrometry (MS) detectors.
- Pump Configuration
- Typically available with binary (two solvent) or quaternary (four solvent) pump options, supporting different gradient elution needs.
- Power Supply
- Requires a standard laboratory power supply, commonly 230V AC, 50/60 Hz in the UK, with specific power consumption varying by modules.
Frequently Asked Questions
- UHPLC (Ultra-High Performance Liquid Chromatography) operates at significantly higher pressures than traditional HPLC, allowing for the use of smaller particle columns. This results in faster separations, improved resolution, and increased sensitivity.
Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.