Steris-Finn Aqua WFI Generation and Storage System

• Production of Water for Injection (WFI) for pharmaceutical formulations and active pharmaceutical ingredient (API) synthesis.
• Supply of high-purity water for cleaning-in-place (CIP) and sterilisation-in-place (SIP) systems in biopharmaceutical facilities.
• Use in laboratory applications requiring endotoxin-free water, such as cell culture media preparation and analytical testing.
• Provision of WFI for sterile manufacturing processes, including injectables and ophthalmic solutions.

Typical WFI Production Capacity

For this class of equipment, production capacities commonly range from 100 to 2,000 litres per hour, depending on the specific model and number of effects.

Storage Tank Volume

WFI storage tanks typically range from 500 to 5,000 litres, designed to maintain WFI quality and supply demand.

Materials of Construction

Product contact parts are typically constructed from 316L stainless steel, with electropolished surfaces for optimal hygiene and corrosion resistance.

Utility Requirements

Units of this type commonly require plant steam (typically 3-8 bar), cooling water, feed water, and instrument air for operation.

Footprint

Skid-mounted systems are designed for a compact footprint, with dimensions varying but typically requiring several square metres of floor space.

Power Supply

Control systems and pumps commonly operate on a 400V, 3-phase, 50Hz supply, with specific power draw depending on pump sizes and heating elements.

Compliance

Systems are typically designed to meet cGMP requirements and produce WFI compliant with USP, EP, and JP pharmacopoeia standards.

• What is multiple-effect distillation?

  Multiple-effect distillation uses a series of evaporators and condensers to generate WFI. The latent heat from the condensing vapour in one effect is used to evaporate water in the next, significantly improving energy efficiency compared to single-effect systems.

• How does this system ensure endotoxin removal?

• Is this system suitable for pharmaceutical validation?

• What maintenance is typically required for a WFI system?

• Can this system be integrated into an existing facility?

WFI generation and storage systems are considered essential infrastructure in pharmaceutical manufacturing. Buyers typically prioritise systems with verified maintenance records, as reliability and consistent water quality are critical. Key considerations include capacity requirements, sanitisation capability, and compliance with relevant pharmaceutical standards. Industry sentiment favours units demonstrating robust construction and proven track records in similar production environments. Used systems often provide good value when sourcing from established manufacturers with documented performance history and complete documentation of previous operating conditions and service schedules.

General overview for this equipment type