Cytiva (formerly part of GE Healthcare Life Sciences) - Cytiva Axichrom 200/300 chromatography column

• Used for the purification of proteins, peptides, and other biomolecules in pharmaceutical and biotechnology research.
• Applied in the production of biopharmaceuticals, including vaccines and therapeutic proteins.
• Utilised for analytical separations and quality control in laboratory settings.
• Essential for downstream processing in biomanufacturing facilities.

Column Diameter

This model number indicates a column diameter of either 200 mm or 300 mm, offering flexibility for different process scales.

Column Material

Typically constructed from robust, biocompatible materials such as stainless steel and borosilicate glass for process integrity.

Operating Pressure

Commonly designed to operate at pressures suitable for high-performance liquid chromatography, typically up to 20 bar.

Operating Temperature

Units of this type are generally rated for operation within a temperature range suitable for biological samples, often 4°C to 30°C.

Typical Bed Volume

Bed volumes can vary significantly based on the column diameter and user-defined bed height, ranging from several litres to tens of litres for this class.

Sealing Mechanism

Features dynamic axial compression (DAC) technology for consistent bed packing and performance, commonly found on units of this type.

• What kind of resins are compatible with the AxiChrom 200/300?

  AxiChrom columns are designed for compatibility with a wide range of chromatography resins, including ion exchange, affinity, and size exclusion media. Buyers should confirm specific resin compatibility with the seller.

• Does this unit come with packing stations or ancillary equipment?

• What maintenance is typically required for a used chromatography column?

• Can this column be validated for GMP manufacturing?

• What is the typical footprint of an AxiChrom 200/300 column?

Chromatography columns and accessories hold strong reputations within analytical laboratories for reliability and consistent performance. Buyers typically value used equipment that maintains original specifications and comes with documentation of maintenance history. Industry sentiment favours purchasing from reputable sources where column condition, packing integrity, and compatibility with existing systems are verified. Common strengths include durability of quality columns across multiple applications and cost savings versus new purchases. When buying used, inspecting for damage, confirming proper storage conditions, and verifying suitability for intended analytical methods remain critical considerations for laboratory operations.

General overview for this equipment type