Cytiva (formerly part of GE Healthcare Life Sciences) - Cytiva Axichrom 70/500 Chromatography Column

• Protein purification in biopharmaceutical production.
• Separation of biomolecules in research and development.
• Pilot-scale purification for process development and scale-up.
• Chromatographic separation of various chemical compounds.
• Downstream processing in biotechnology and food industries.

Column Diameter

Typically 70 mm for this model, indicating suitability for pilot-scale operations.

Column Length

Commonly 500 mm, allowing for a significant bed height and separation efficiency.

Operating Pressure

Units of this type are designed for pressures typically up to 20 bar (290 psi), depending on the specific packing material and application.

Material of Construction

Wetted parts are commonly made from 316L stainless steel and biocompatible polymers (e.g., PEEK, PTFE) for chemical resistance and hygiene.

Temperature Range

Typically designed to operate safely within a range of 4°C to 40°C, suitable for biological samples.

Flow Rate

Maximum flow rates are dependent on the column diameter and packing, but for this class, they typically support process-relevant flow rates for pilot-scale purification.

Sealing Mechanism

Often features a hydraulic or pneumatic piston for efficient and reproducible bed compression.

• What is the typical bed volume for an AxiChrom 70/500 column?

  The bed volume for an AxiChrom 70/500 column can vary depending on the packed bed height, but for a 500mm length, it typically ranges from approximately 1.5 to 2 litres.

• Is this column suitable for GMP environments?

• What type of chromatography media can be used with this column?

• What maintenance is typically required for a chromatography column of this type?

• Can this column be automated?

Chromatography columns and accessories hold strong reputations within analytical laboratories for reliability and consistent performance. Buyers typically value used equipment that maintains original specifications and comes with documentation of maintenance history. Industry sentiment favours purchasing from reputable sources where column condition, packing integrity, and compatibility with existing systems are verified. Common strengths include durability of quality columns across multiple applications and cost savings versus new purchases. When buying used, inspecting for damage, confirming proper storage conditions, and verifying suitability for intended analytical methods remain critical considerations for laboratory operations.

General overview for this equipment type