Willemse & Van Engelen - GE AxiChrom 100/300 Chromatography Colum

• Protein purification in pharmaceutical research and development.
• Bioprocess scale-up and manufacturing of biologics.
• Separation of biomolecules in academic and industrial laboratories.
• Chromatographic method development and optimisation.

Column diameter

Typically 100 mm for this model, indicating suitability for pilot to small-scale production.

Column length

Commonly 300 mm, allowing for a bed volume suitable for various purification tasks.

Pressure rating

Units of this type typically operate at pressures up to 20 bar, depending on the specific packing material.

Materials of construction

Wetted parts are commonly 316L stainless steel and biocompatible polymers, ensuring chemical resistance and hygiene.

Temperature range

Typically designed for operation between 4°C and 40°C, accommodating most bioprocessing requirements.

Flow rate

Throughput for this class of column is typically in the range of 10-100 L/hr, depending on resin and application.

• What is an AxiChrom column used for?

  AxiChrom columns are primarily used for preparative chromatography, specifically for the purification of proteins, peptides, and other biomolecules in laboratory and bioprocess environments.

• What are the key benefits of the AxiChrom design?

• Is this column suitable for cGMP environments?

• What kind of resins can be used with this column?

• What maintenance is typically required for an AxiChrom column?

Chromatography columns and accessories hold strong reputations within analytical laboratories for reliability and consistent performance. Buyers typically value used equipment that maintains original specifications and comes with documentation of maintenance history. Industry sentiment favours purchasing from reputable sources where column condition, packing integrity, and compatibility with existing systems are verified. Common strengths include durability of quality columns across multiple applications and cost savings versus new purchases. When buying used, inspecting for damage, confirming proper storage conditions, and verifying suitability for intended analytical methods remain critical considerations for laboratory operations.

General overview for this equipment type