GE Healthcare UniFlux 120 TFF System

• Biopharmaceutical processing for clarification and concentration.
• Monoclonal antibody purification and vaccine production.
• Protein concentration and buffer exchange in biotech.
• Pilot to manufacturing-scale operations requiring precise filtration.

Typical flow rate

For this class of equipment, flow rates commonly range from 12 to 120 litres per minute.

Membrane compatibility

Units of this type typically support both cassette and hollow fibre membranes.

Control system

Commonly integrated with UNICORN software for automation and data logging.

Pump type

Often features a rotary lobe pump for precise flow control.

Construction materials

Typically constructed from stainless steel for sanitary and GMP compliance.

Power supply

Units of this nature commonly require a three-phase industrial power supply, typically 400V.

Footprint

For systems designed for pilot to manufacturing scale, a significant industrial footprint is typical.

• What is Tangential Flow Filtration (TFF)?

  TFF is a filtration method where the feed stream flows tangentially across the membrane surface, rather than perpendicularly. This minimises membrane fouling and allows for continuous processing, making it ideal for concentrating and purifying biomolecules.

• What are the main applications of a UniFlux 120 TFF system?

• Can this system be used with different membrane types?

• Is the system suitable for GMP environments?

• What software is typically used to control this system?

• What level of automation can be expected?

Separators and extraction systems are valued for their reliability in sample preparation workflows across laboratory and pharmaceutical settings. Buyers typically seek equipment with robust construction and minimal downtime history. Key considerations when purchasing used units include chamber integrity, seal condition, and calibration documentation. Industry sentiment favours models offering consistent reproducibility and easy maintenance. Established brands generally command confidence due to parts availability and technical support, though thorough inspection and performance testing remain essential before purchase.

General overview for this equipment type