What is tangential flow filtration (TFF)?

TFF is a filtration method where the feed fluid flows tangentially across the surface of the membrane, rather than perpendicularly. This minimises membrane fouling and allows for continuous processing.

What is diafiltration?

Diafiltration is a TFF process used to exchange buffers or reduce the concentration of small molecules in a solution. It involves adding fresh buffer to the feed stream while simultaneously removing permeate.

Can this system be used with different membrane types?

Systems of this nature are typically compatible with various hollow fibre filters and flat sheet cassettes, allowing flexibility in membrane pore size and material for different applications.

Is this unit suitable for GMP environments?

While versatile for R&D, specific GMP suitability depends on the unit's exact configuration, documentation, and validation status. Buyers should verify these details with the seller.

What maintenance is typically required for a TFF system?

Routine maintenance usually involves cleaning and sanitising fluid paths and membranes after use, along with periodic inspection and replacement of tubing and seals. Calibration of pumps and sensors may also be required.

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Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 1

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 2

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 3

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 4

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 5

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 6

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 7

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 8

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 9

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 10

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems, photo 11

Used Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration - Separators & Extraction Systems

used Equipment

Available

Verified seller

Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration

Name: Spectrum Labs KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration
Brand: Spectrum Labs
SKU: 49123
Availability: InStock

Price: Contact seller for price

This listing is for the Spectrum Labs KrosFlow KR2i TFF System.

The unit is in full working condition and is ready for immediate release.

The KR2i TFF System is a versatile tangential flow filtration system, suitable for running volumes from 2 mL up to 10 L.

It consists of a pump, tablet controller, scale, module stand, and real-time data collection software.

The KR2i can mount up to two pump heads, allowing users to add an additional one if desired.

Key Features of KR2i TFF System:

Hollow fiber filter for 2 mL to 10 L.
Flat sheet cassettes can process 12 mL to 15 L.
Auxiliary pump (900-1893): 600 RPM.
SAW-KR21 Scale: Capacity up to 20 kg with readability of 0.2 g.
Scale platform size: 18 x 18 cm.
Tablet control for ease of operation and real-time monitoring.
IP33-rated plastic enclosure is easy to clean.
Assortment of accessories included (see photos).

The KR2i pump is designed to handle abrasive slurries, corrosive fluids, and highly viscous fluids with minimal wear.

The system ensures that the fluid only comes into contact with the tubing and tube material, eliminating valves that could clog and making the inner surfaces easy to clean.

With its compact footprint and versatility, the KR2i is an ideal choice for small-volume, R&D-scale microfiltration and ultrafiltration.

Cambridgeshire, United Kingdom

5,773 km away

Model Number

KrosFLO TFF System KMPi Auxiliary Pump for Diafiltration

Stock Number

49123

Machinery Masters View

Typical context for this category of equipment. Always confirm specifics with the seller.

Concentration and diafiltration of proteins, viruses, and nanoparticles in biopharmaceutical research.
Clarification of cell cultures and fermentation broths in laboratory settings.
Small-scale purification and separation of biomolecules in academic and industrial R&D.
Process development for scaling up tangential flow filtration operations.

Typical processing volume: For this class of system, volumes typically range from a few millilitres up to 10-15 litres.
Pump type: Units of this type commonly feature peristaltic pumps, suitable for handling various fluid viscosities and minimising shear.
Filtration mode: This equipment is designed for tangential flow filtration, supporting both microfiltration and ultrafiltration applications.
Control interface: Modern TFF systems often include integrated or tablet-based controllers for real-time monitoring and parameter adjustment.
Power supply: Typically operates on standard single-phase laboratory power, commonly 230V, 50Hz in the UK.
Footprint: Designed for benchtop use, units of this type typically have a compact footprint suitable for laboratory environments.

TFF is a filtration method where the feed fluid flows tangentially across the surface of the membrane, rather than perpendicularly. This minimises membrane fouling and allows for continuous processing.

Separators and extraction systems are valued for their reliability in sample preparation workflows across laboratory and pharmaceutical settings. Buyers typically seek equipment with robust construction and minimal downtime history. Key considerations when purchasing used units include chamber integrity, seal condition, and calibration documentation. Industry sentiment favours models offering consistent reproducibility and easy maintenance. Established brands generally command confidence due to parts availability and technical support, though thorough inspection and performance testing remain essential before purchase.

General overview for this equipment type

Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.