Cytiva Sweden AB - AKTA Ready Chromatography System

• Biopharmaceutical manufacturing, particularly for monoclonal antibodies and recombinant proteins.
• Viral vector and nucleic acid purification in gene therapy and vaccine production.
• Process scale-up and development for new biological entities.
• GMP-regulated manufacturing environments requiring high purity and minimal cross-contamination.
• Production of sensitive therapeutic products where single-use technology is advantageous.

Typical flow rate range

Units in this class commonly offer flow rates from tens of millilitres per minute up to several litres per minute, depending on the flow kit installed.

Operating pressure

Typically designed for pressures suitable for process-scale chromatography, often up to 0.5 MPa (5 bar).

Power supply

Commonly requires a standard industrial single-phase supply, typically 100-240 VAC, 50/60 Hz.

Footprint

For this class of equipment, units are designed for integration into bioprocessing suites, with a footprint that can vary based on configuration but is generally compact for its capacity.

Material compatibility

The single-use flow paths are typically constructed from biocompatible plastics, such as polypropylene and polyethylene, suitable for pharmaceutical contact.

Control system

Units of this type are typically controlled via integrated software, offering comprehensive method development and run control.

Maintenance requirements

Due to single-use flow paths, routine cleaning and cleaning validation are eliminated, significantly reducing maintenance related to product contact parts.

• What is the primary benefit of a single-use chromatography system?

  The main benefit is the elimination of cleaning and cleaning validation between runs, which reduces downtime, minimises cross-contamination risk, and simplifies GMP compliance.

• Can this system be used for different purification methods?

• Is this equipment suitable for GMP environments?

• What kind of consumables does this system use?

• How scalable is the ÄKTA ready platform?

Chromatography systems command strong respect within analytical and pharmaceutical sectors. Buyers typically prioritise equipment with verified maintenance records and clear calibration history, as these directly affect analytical accuracy. Used units from established manufacturers remain highly valued for their reliability. Key strengths include reproducible results, robust construction, and established spare parts availability. Industry sentiment reflects confidence in these systems when sourced from reputable suppliers with transparent service documentation.

General overview for this equipment type