Cytiva Sweden AB - Akta ready™ Chromatography System

Applications & Use Cases

• Biopharmaceutical manufacturing of monoclonal antibodies and recombinant proteins.
• Production of viral vectors and nucleic acids for gene therapies.
• Process scale-up and development in biotechnology.
• GMP-regulated manufacturing of sensitive therapeutic products.
• Purification of various biologics in a controlled environment.

Typical Specifications

Typical flow rate range

Units in this class commonly offer a broad flow rate range, typically from tens of millilitres per minute up to several litres per minute, depending on the specific flow kit installed.

Operating pressure

For this type of chromatography system, operating pressures are typically in the range of 0.5 to 1.5 MPa (5 to 15 bar).

Power supply

Commonly requires a standard industrial single-phase power supply, typically 230V, 50Hz for the UK market.

Temperature control

Often includes or supports temperature control features for maintaining optimal process conditions, typically ambient to 40°C.

UV detection wavelengths

Units of this type commonly feature variable UV detection, typically covering wavelengths from 190 nm to 700 nm.

Footprint

While specific dimensions vary, these systems are generally designed for laboratory or small-scale production environments, requiring a dedicated bench or floor space of approximately 0.5 to 1 square metre.

Materials in contact with product

For single-use systems like this, all product-wetted parts are typically made from biocompatible, disposable plastics such as polypropylene or polyethylene.

Frequently Asked Questions

• What are the primary benefits of a single-use chromatography system?

  Single-use systems eliminate the need for cleaning and cleaning validation, significantly reducing downtime between runs and minimising the risk of cross-contamination. This is particularly beneficial in GMP environments.

• Is this system suitable for GMP manufacturing?

• Can this system be scaled for different production volumes?

• What types of purification methods can this system perform?

• What maintenance is typically required for a single-use system?