What is Tangential Flow Filtration (TFF)?

TFF is a filtration method where the feed stream flows tangentially across the surface of a membrane, rather than perpendicularly through it. This minimises membrane fouling and allows for continuous processing.

What are the primary benefits of using a TFF system like the Pro Flux M30?

Key benefits include efficient concentration and diafiltration, scalability, reduced membrane fouling compared to dead-end filtration, and suitability for processing shear-sensitive biomolecules.

Can this system be used for both research and production?

Units of this model are typically designed for laboratory and pilot-scale operations, with inherent scalability to larger production environments, making them versatile for various stages of development.

What kind of maintenance does a TFF system require?

Routine maintenance typically involves cleaning-in-place (CIP) and storage procedures for membranes, periodic calibration of sensors, and inspection of pumps and tubing for wear.

Is this system suitable for sterile applications?

Given its stainless steel construction and design, this class of equipment is generally suitable for aseptic operation and can be integrated into sterile processing workflows, often requiring sterilisation-in-place (SIP) capabilities.

Used Millipore Pro Flux M30 Tangential Flow Filtration System - Separators & Extraction Systems, photo 1

Used Millipore Pro Flux M30 Tangential Flow Filtration System - Separators & Extraction Systems, photo 2

Used Millipore Pro Flux M30 Tangential Flow Filtration System - Separators & Extraction Systems, photo 3

Used Millipore Pro Flux M30 Tangential Flow Filtration System - Separators & Extraction Systems, photo 4

Used Millipore Pro Flux M30 Tangential Flow Filtration System - Separators & Extraction Systems, photo 5

Used Millipore Pro Flux M30 Tangential Flow Filtration System - Separators & Extraction Systems

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Available

Verified seller

Millipore - Millipore Pro Flux M30 Tangential Flow Filtration System

Name: Millipore Pro Flux M30 Tangential Flow Filtration System
Brand: Millipore
SKU: 26611

Price: Contact seller for price

This listing is for a Millipore Pro Flux M30 Tangential Flow Filtration (TFF) System. The unit is in full working condition and is ready for immediate release. The Millipore Pro Flux M30 is a high-performance tangential flow filtration (TFF) system designed for demanding applications in the biotechnology, pharmaceutical, and molecular diagnostics sectors. Optimized for crossflow filtration, the M30 provides reliable separation, concentration, and clarification of biomolecules and cell suspensions in both R&D and process-scale environments. With its robust stainless steel construction, precise transmembrane pressure (TMP) control, and compatibility with a wide range of membrane chemistries, the M30 delivers consistent performance across various filtration tasks—from protein concentration and virus clarification to cell culture harvest and synthetic biology sample prep.

Cambridgeshire, United Kingdom

5,791 km away

Model Number

Pro Flux M30

Stock Number

26611

Machinery Masters View

Typical context for this category of equipment. Always confirm specifics with the seller.

Applications & Use Cases

Concentration and diafiltration of proteins, antibodies, and vaccines.
Clarification of cell cultures and fermentation broths.
Virus filtration and removal in biopharmaceutical manufacturing.
Sample preparation for analytical and purification steps.
Buffer exchange and desalting of biomolecules.

Typical Specifications

Typical capacity: For this class of system, it typically handles volumes from 1 to 30 litres, depending on membrane area and application.
Power supply: Commonly requires a standard single-phase electrical supply, typically 230V, 50Hz for UK operation.
Membrane compatibility: Units of this type are compatible with a wide range of flat sheet or hollow fibre membranes from various manufacturers, offering flexibility in molecular weight cut-offs and chemistries.
Construction material: Typically features wetted parts constructed from 316L stainless steel and sanitary elastomers, suitable for pharmaceutical applications.
Control system: Commonly includes integrated controls for transmembrane pressure (TMP), flow rate, and temperature, often with a user-friendly interface.
Footprint: For a laboratory-scale unit, the footprint is typically compact, designed for benchtop or mobile cart placement.

Frequently Asked Questions

TFF is a filtration method where the feed stream flows tangentially across the surface of a membrane, rather than perpendicularly through it. This minimises membrane fouling and allows for continuous processing.

Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.