What is the primary advantage of UPLC over traditional HPLC?

UPLC (Ultra-Performance Liquid Chromatography) offers significantly faster separations, higher resolution, and increased sensitivity compared to conventional HPLC, due to its ability to operate at much higher pressures with smaller particle size columns.

Is this system suitable for method transfer from existing HPLC methods?

Yes, the Waters ACQUITY UPLC H-Class system is designed with method transfer in mind, often allowing for seamless scaling of existing HPLC methods to UPLC conditions while maintaining chromatographic integrity.

What kind of maintenance does a UPLC system typically require?

Routine maintenance typically includes replacing pump seals, check valves, and autosampler syringes, as well as cleaning or replacing detector lamps and flow cells. Regular solvent and system flushing is also crucial.

Are spare parts and consumables readily available for Waters ACQUITY UPLC systems?

Yes, Waters is a major manufacturer, and spare parts and consumables for ACQUITY UPLC systems are generally widely available through Waters directly or authorised distributors.

What software is typically used to operate a Waters ACQUITY UPLC system?

Waters ACQUITY UPLC systems are typically operated using Waters Empower software, which provides comprehensive control, data acquisition, and data processing capabilities.

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 1

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 2

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 3

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 4

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 5

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 6

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 7

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 8

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 9

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 10

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 11

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 12

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC)

used Equipment

Available

Verified seller

Waters Acquity UPLC

Name: Waters Acquity UPLC
Brand: Waters
SKU: 25361.8B
Price: 4500 GBP
Availability: InStock

Price: £ 4,500

Used Waters ACQUITY UPLC system delivering high-resolution, reliable liquid chromatography for advanced analytical laboratory applications.

Cambridgeshire, United Kingdom

5,773 km away

Model Number

Aquity H-Class

Stock Number

25361.8B

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Typical context for this category of equipment. Always confirm specifics with the seller.

Pharmaceutical analysis for drug discovery, development, and quality control.
Environmental testing for pollutants in water, soil, and air samples.
Food and beverage analysis for contaminants, additives, and nutritional components.
Clinical research for biomarker discovery and disease diagnosis.
Chemical and petrochemical industries for process monitoring and product characterisation.

Typical pressure range: Up to 15,000 psi (1034 bar) for this class of UHPLC equipment.
Flow rate range: Commonly 0.01 to 2.0 mL/min, suitable for narrow-bore columns.
Detector options: Typically compatible with various detectors including UV/Vis, PDA, FLR, and MS.
Sample capacity: Autosamplers often accommodate multiple well plates or up to 100+ vials.
Power supply: Typically requires a standard laboratory power supply, commonly 230V, 50Hz in the UK.
Footprint: Modular design, but a complete system (pump, autosampler, detector) typically occupies a significant bench space.

UPLC (Ultra-Performance Liquid Chromatography) offers significantly faster separations, higher resolution, and increased sensitivity compared to conventional HPLC, due to its ability to operate at much higher pressures with smaller particle size columns.

Chromatography systems command strong respect within analytical and pharmaceutical sectors. Buyers typically prioritise equipment with verified maintenance records and clear calibration history, as these directly affect analytical accuracy. Used units from established manufacturers remain highly valued for their reliability. Key strengths include reproducible results, robust construction, and established spare parts availability. Industry sentiment reflects confidence in these systems when sourced from reputable suppliers with transparent service documentation.

General overview for this equipment type

Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.