What is the primary advantage of UPLC over traditional HPLC?

UPLC (Ultra-Performance Liquid Chromatography) offers significantly faster separations, higher resolution, and increased sensitivity compared to traditional HPLC, primarily due to its use of smaller particle size columns and higher operating pressures.

Is specific software required to operate this Waters Acquity UPLC?

Yes, Waters UPLC systems typically require proprietary Waters Empower or MassLynx software for instrument control, data acquisition, and analysis. Buyers are responsible for software licensing.

What kind of maintenance does a UPLC system require?

Routine maintenance typically involves replacing solvent filters, pump seals, check valves, and injector components. Column care and regular system flushing are also crucial for optimal performance.

Can this unit be integrated with other laboratory equipment?

Waters Acquity UPLC systems are commonly integrated with various detectors, including mass spectrometers (LC-MS), and can often be connected to laboratory automation systems for high-throughput applications.

What consumables are needed for operation?

Operation requires UPLC-grade solvents, appropriate analytical columns, vials, and potentially specific mobile phase additives. These are typically not included with the instrument.

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Waters Acquity UPLC

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 1

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 2

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 3

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 4

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 5

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 6

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 7

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 8

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 9

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 10

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 11

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 12

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC), photo 13

Used Waters Acquity UPLC - Chromatography Systems (HPLC, UHPLC, GC, LCMS, GPC-SEC)

used Equipment

Available

Verified seller

Waters Acquity UPLC

Name: Waters Acquity UPLC
Brand: Waters
SKU: 25361.8B
Price: 4500 GBP
Availability: InStock

Price: £ 4,500

This listing is for Waters Acquity UPLC.

The unit is in full working condition and ready for immediate use.

The Waters Acquity UPLC is an ultra performance liquid chromatography system designed for rapid, high resolution analytical separations.

It delivers excellent sensitivity, reproducibility, and solvent efficiency for pharmaceutical, biotechnology, environmental, food, and research laboratory applications.

Transparency Report and Technical Audit

Software and Media Disclosure:

As a Direct-from-Lab asset, any original software media or accessories found with the unit are included as a courtesy.

Licensing Notice: We do not provide, transfer, or guarantee software licenses or keys.

The buyer is responsible for all software licensing, registration, and workstation compatibility via the manufacturer.

Notice for Procurement:

This unit is sold As-Is.

While we verify the power-on status and physical integrity, we do not perform analytical validation, fluidic testing, or operational calibration.

Ideal for labs with in-house technical expertise or existing service agreements.

Sustainability Impact:

By choosing Direct Reuse, your facility avoids the carbon footprint of new manufacturing and prevents specialized materials from entering waste streams.

Direct-to-Lab reuse is the most carbon-efficient way to equip a modern laboratory.

Cambridgeshire, United Kingdom

5,773 km away

Model Number

Aquity H-Class

Stock Number

25361.8B

Machinery Masters View

Typical context for this category of equipment. Always confirm specifics with the seller.

Pharmaceutical analysis for drug discovery, development, and quality control.
Biotechnology for protein and peptide analysis, and biomarker discovery.
Environmental testing for pollutant detection and water quality assessment.
Food and beverage analysis for quality control, contaminant detection, and nutritional profiling.
Academic and industrial research for complex mixture separations and method development.

Typical pressure range: Units of this type commonly operate at pressures up to 15,000 psi (1000 bar) or higher.
Flow rate range: For this class of equipment, flow rates typically range from 0.01 to 2.0 mL/min.
Detector options: Commonly integrated detectors include UV/Vis, PDA, fluorescence, and mass spectrometry (MS) compatibility.
Column compatibility: Designed for use with sub-2µm particle size columns, typically 50-150 mm in length.
Solvent channels: Often features binary, ternary, or quaternary solvent management systems.
Power supply: Typically requires a standard laboratory power supply, commonly 230V, 50Hz in the UK.
Footprint: The modular design of UPLC systems allows for a relatively compact footprint for high-performance analysis.

UPLC (Ultra-Performance Liquid Chromatography) offers significantly faster separations, higher resolution, and increased sensitivity compared to traditional HPLC, primarily due to its use of smaller particle size columns and higher operating pressures.

Chromatography systems command strong respect within analytical and pharmaceutical sectors. Buyers typically prioritise equipment with verified maintenance records and clear calibration history, as these directly affect analytical accuracy. Used units from established manufacturers remain highly valued for their reliability. Key strengths include reproducible results, robust construction, and established spare parts availability. Industry sentiment reflects confidence in these systems when sourced from reputable suppliers with transparent service documentation.

General overview for this equipment type

Machinery Masters Intelligence. General guidance for this category of equipment only, not a substitute for the seller's exact specifications. Always confirm details with the seller.