Waters fraction Collector 111 chromatography system - Waters Acquity H-Class UPLC System

Applications & Use Cases

• Pharmaceutical research and quality control for drug discovery and purity analysis.
• Biotechnology for protein and peptide analysis, and biomarker identification.
• Food and beverage analysis for contaminants, additives, and nutritional components.
• Environmental testing for pollutants, pesticides, and water quality assessment.
• Chemical analysis for complex mixture separations and compound identification.

Typical Specifications

Typical Flow Rate Range

Typically 0.01 to 2.00 mL/min, suitable for high-resolution separations.

Maximum System Pressure

Commonly up to 15,000 psi (1034 bar), enabling the use of sub-2µm particle columns.

Solvent Blending

Typically features quaternary solvent blending for method development flexibility.

Detector Type

This unit includes a TUV Detector; other common options for this class include PDA, FLR, and MS detectors.

Sample Capacity

Sample managers for this type of system commonly accommodate multiple well plates or numerous vials.

Power Supply

Typically requires a standard laboratory power supply, often 230V, 50/60Hz for UK operation.

Footprint

For this class of equipment, a typical UPLC system requires significant bench space, often comprising multiple modules.

Frequently Asked Questions

• What is the primary advantage of a UPLC system over a traditional HPLC?

  UPLC (Ultra-Performance Liquid Chromatography) systems operate at higher pressures with smaller particle columns, leading to significantly faster analysis times, improved resolution, and enhanced sensitivity compared to traditional HPLC.

• Can existing HPLC methods be transferred to this UPLC system?

• Is software included with this UPLC system?

• What kind of maintenance does a UPLC system typically require?

• What are the common detectors used with UPLC systems?